All Allele Registry Extension APIs News

Allele Registry Extension APIs

fix

Fixed Coorinate Transform Logic

8.16.3

2026-02-16

  • Fixed coordinate transform logic for cases where CAR doesn't include the originally provided coorindates, but includes lifted coordinates to alternative assemblies.

Allele Registry Extension APIs

feature

Code update

8.16.0

2026-02-11

  • Updated dependencies to use latest fastify version.

Allele Registry Extension APIs

feature

SV prefix search

8.15.1

2026-02-06

  • Added SV prefix search endpoint GET /sv/desc?search=grch38.
  • Added HT repair script to repair haplotype registrations where not all edges were created.
  • Fixed overlapping count endpoint for sv-reg, loc-reg, and ht-reg to return correct count by using same max limit as overlapping endpoint.

Allele Registry Extension APIs

feature

License and Terms of Use service endpoints

8.14.0

2025-12-30

  • Added License and Terms of Use plugins.

Allele Registry Extension APIs

feature

Add Haplotype Registry and various features to CAR extension services.

8.13.0

2025-12-30

  • Added Haplotype Registry.
  • Added GET /desc/:desc/normalized and POST /desc/normalized routes to all car extension services.
  • Added GET /mq/sse/evts/requests for event source of requests made to a car extension services.
  • Added POST /mq/sse/evts/reg to produce reg events.
  • Added asymmetric coordinate support to SV and GL registry. This allows registration of descriptors with a mix of precise and imprecise coordinates.
  • Added SV type filter support to GET /sv/desc/:desc/overlapping with the ?types query parameter.
  • Added prefix search for PGX alleles .e.g. GET /pgx/id/?search=NUDT.
  • Added count endpoint to to all sv-reg, loc-reg, and ht-reg overlap endpoints e.g. GET /sv/desc/:desc/overlapping/count.
  • Enable toggle of CORS for cases where reverse proxy already handles it.

Allele Registry Extension APIs

feature

Add prefix search for HLA descriptors.

8.1.3

2025-06-09

  • Added prefix search for HLA allele descriptors.
  • Fixed subtle bug preventing SSEs from being emitted caused by mis-management of queue for requests.

Allele Registry Extension APIs

feature

Add PGX Registry

8.0.0

2025-04-24

  • Add Cligen PGX Registry.
  • Change HLA namespace from CAHLA to XAHLA.

Allele Registry Extension APIs

fix

Fix loc-reg duplicates

N/A

2025-03-21

  • Fixed loc-reg duplicates.
  • Deployed to cloud VMs.

Allele Registry Extension APIs

fix

Fixed Descriptor Registration Logic

6.10.0

2025-03-11

  • Fixed the descriptor registration logic for aber, sv, and loc services to prevent duplicate registration.
  • Unified single and batch descriptor transform.
  • Improved error logging.

Allele Registry Extension APIs

feature

Added support for batch descriptor registration.

6.8.2

2025-02-05

  • Sv, Aber, Loc, and HLA descriptors can now be registered in batches and concurrently.
  • Enforced 1-based fully closed range validation for Sv and Loc descriptors.
  • Fixed format of logged errors.
  • Improved error response messages.
  • Improved handling of network errors from AR service.

Allele Registry Extension APIs

feature

Support GET /$/*, GET /?fields, and GET /id/ for all services.

6.5.1

2024-10-17

Allele Registry Extension APIs

fix

Improve request client error handling and descriptor normalization

6.4.0

2024-10-11

  • Fixed max retry, base sleep, and timeout request client issues and made them configurable.
  • Fixed descriptor normalization of chrM to chrMT.

Allele Registry Extension APIs

feature

Use Independent Coordinate Transform

6.3.1

2024-09-19

  • Remove database transaction queries.
  • Add concurrency handling for parallel descriptor registration for improved service robustness and data integrity.

Allele Registry Extension APIs

fix

Fix Descriptor Registration AQL Logic

6.0.17

2024-07-01

Allele Registry Extension APIs

feature

Add HLA Registry

6.0.11

2024-05-28

Allele Registry Extension APIs

feature

Add Count Summary

5.2.1

2024-04-01

  • Added count summary to sv, ab, and gl service's GET /srvc routes.

Allele Registry Extension APIs

feature

Deploy SV, AB, and GL Registries.

5.0.5

2024-02-26

  • Deployed Genomic Structural Variant Registry.
  • Deployed Genomic Aberration Registry.
  • Deployed Genomic Location Registry.
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